In our projects we tend to have a large number of sounds that need to have the same pan / channel settings (for example, UI sounds). These settings get copied as you duplicate events, but if you want to change these later, multi-edit doesn’t seem to always work as expected.
As a suggestion, I think presets for channel Input and Output panner settings would be quite useful. You could include automation for these as well.
As a workaround so far I’ve used a 3D Panner preset with 100% Pan Override to have a specific pan setup for a group of events, but this does not let me enable/disable speakers or channels in the panner.
Whether the incoming signal is mono or stereo (leading to either L/R or Distributed surronud) may cause edge cases here, but maybe that’s solveable.