When ever upgrading a major version it’s worth check the appropriate “what’s new” section of the API and Studio documentation. I wouldn’t consider the upgrade dangerous, but you should always use caution when taking a new major versions.
If you game is near shipping, this is not a good idea, but if you have plenty of development time left then upgrading off the now unsupported 1.10 branch is a good idea.
EDIT: It’s worth noting that although it looks scary 1.10 -> 2.00, we treat it the same as 1.09 -> 1.10 from a compatibility standpoint.